Jan 23, 2018 | Updated: 09:54 AM EDT

These Nanosponges Can Reduce Life-threatening Streptococcal Infections

Apr 27, 2017 04:46 PM EDT

Nansponges are now showcasing life-saving capacity. A group of researchers recently innovated such an engineered nanosponges which, being encoded in the red blood cell membranes, can fight out the severity of infections caused by group A Streptococcus, a harmful bacteria which is responsible for strep throat and necrotizing fasciitis or flesh-eating disease. The innovation is expected to pave new pathways for the effective treatment of certain antibiotic-resistant bacterial infections.

According to Science Daily, group A Streptococcus alongside other similar pathogens actually release severe and dangerous type pore-forming toxins which can push to make holes within the affected one's cell's membrane, slightly turning it to cell death. The researchers' group created this nanosponge by a pulling out the remembrance alongside other contents from the red blood cells and thereby engineered a dedicated core to absorb the dangerous toxins generated by those pathogens. The experiment actually worked. The nanosponges debarred the toxins from reaching out to the cell membranes of certain sensitive cell units like skin cells and white blood cells etc.

As per another report by Phys, the nanosponges showcased its fruitful effects on cultured cells. Tamara Escajadillo, graduate student researcher at the University of California in San Diego, who has been an important participant in this study, while speaking about the activity of this nanosponges, stated: "By demonstrating their effectiveness with live Streptococcal infections, we provide compelling evidence for the potential functionality of the nanosponges in a clinical setting."   

The team is now said to examine the effects on the nanosponges on various other bacteria and pathogens as well. They are also attempting to find out new technique to a sharpen the effects of the nanosponges on other harmful factors as well. Escajadillo will present this patent at the American Society for Pharmacology and Experimental Therapeutics annual meeting during the Experimental Biology 2017 meeting, which has been scheduled to be held April 22, 2017- April 26, 2017 in Chicago. 

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