MEDICINE & HEALTHChildren and young adults with cystic fibrosis (CF) whose lung infections were treated with suboptimal doses of antibiotics had fewer changes in lung microbial diversity during the IV treatment, and their microbial diversity levels were higher 30 days later, a multi-institutional study that includes Children's researchers shows.
A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.
Despite challenges, new advances in stem cell biology and genetic engineering show potential for better cell replacement therapies, say experts in a special supplement to the Journal of Parkinson's Disease
Researchers at the University of California, Irvine have developed a wearable, disposable respiration monitor that provides high-fidelity readings on a continuous basis. It's designed to help children with asthma and cystic fibrosis and others with chronic pulmonary conditions.
A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells. The work could inspire new approaches to treating patients and inhibiting tumor growth.
A team of physicists from Immanuel Kant Baltic State University suggested a method to quickly identify single antibiotic-resistant bacteria cells that are the agents of tuberculosis. The new method helps find the bacteria and evaluate their resistance to antibiotics without damaging the biological material. The results of the first trial of the method were published in Data in Brief.
Scientists in Canada have developed a new method for preventing and treating chlamydia. Chlamydia, caused by Chlamydia trachomatis, is a common sexually transmitted disease that can infect women with cervicitis and in both men and women with urethritis and proctitis. The team of researchers from the University of Waterloo treats chlamydia through gene therapy using nanotechnology.
A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent.
International team of 27 authors is first to link DNA variants in IRF6 to this common birth defect Mutations in a gene known as interferon regulatory factor 6 (IRF6) that cause cleft lip and palate also are implicated in neural tube defects such as spina bifida, suggests research by an international study team published online Jan.
New research shows that extra nuclei gained during exercise persist even after a muscle shrinks from disuse, disease or aging -- and can be mobilized rapidly to facilitate bigger gains on retraining
Fitness goals are typically at the forefront of new year's resolutions for many Americans, and a recent study from ASU provides a new way to understand diet and exercise in a more holistic way, and may help us reach those goals.
Growing muscle tissue on grooved platforms helps neurons more effectively integrate with the muscle, a requirement for engineering muscle in the lab that responds and functions like muscle in the body, University of Illinois researchers found in a new study.
US doctors who receive direct payments from opioid manufacturers tend to prescribe more opioids than doctors who receive no such payments, according to new research published by Addiction.