MEDICINE & HEALTH

ZEB1, Oscar for leading role in fat storage

A team from EPFL, in collaboration with ETH Zurich, has managed to decode the process of adipogenesis by identifying the precise proteins that play the leading roles in fat absorption. Their findings have been published in the open-access scientific journal eLife.

New drug-delivery capsule may replace injections

Given a choice, most patients would prefer to take a drug orally instead of getting an injection. Unfortunately, many drugs, especially those made from large proteins, cannot be given as a pill because they get broken down in the stomach before they can be absorbed.

Fibromyalgia and the role of brain connectivity in pain inhibition

The cause of fibromyalgia, a chronic pain syndrome is not known. The cause of fibromyalgia, a chronic pain syndrome is not known. However, the results of a new study that compares brain activity in individuals with and without fibromyalgia indicate that decreased connectivity between pain-related and sensorimotor brain areas could contribute to deficient pain regulation in fibromyalgia, according to an article published in Brain Connectivity, a peer-reviewed journal from Mary Ann Liebert, Inc.

New learning mechanism for individual nerve cells

The traditional view is that learning is based on the strengthening or weakening of the contacts between the nerve cells in the brain. However, this has been challenged by new research findings from Lund University in Sweden. These indicate that there is also a third mechanism – a kind of clock function that gives individual nerve cells the ability to time their reactions.

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants

TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch TAU researcher harnessaes gold nanoparticles to engineer novel biocompatible cardiac patch Because heart cells cannot multiply and cardiac muscles contain few stem cells, heart tissue is unable to repair itself after a heart attack.

Americans undergo colonoscopies too often, study finds

Following the proper guidelines could save money and discomfort of unnecessary screenings Following the proper guidelines could save money and discomfort of unnecessary screenings Colonoscopies are a very valuable procedure by which to screen for the presence of colorectal cancer.

NEJM: Crizotinib Effective in Phase 1 Trial Against ROS1 Lung Cancer

The New England Journal of Medicine reports positive results of a phase 1 clinical trial of the drug crizotinib against the subset of lung cancer marked by rearrangement of the gene ROS1. In this multi-center study of 50 patients with advanced non-small cell lung cancer testing positive for ROS1 gene rearrangement, the response rate was 72 percent, with 3 complete responses and 33 partial responses. Median progression-free survival – the time it takes for the disease to resume its growth after being slowed by treatment – is estimated at 19.2 months with exactly half of patients remaining on observation for disease progression that has not yet occurred.

Antioxidant found in grapes uncorks new targets for acne treatment

UCLA study points to resveratrol as key to possible combination therapy UCLA study points to resveratrol as key to possible combination therapy Got grapes? UCLA researchers have demonstrated how resveratrol, an antioxidant derived from grapes and found in wine, works to inhibit growth of the bacteria that causes acne.

New hypothyroidism treatment guidelines from American Thyroid Association

Published in Thyroid journal Published in Thyroid journal New Rochelle, NY, September 30, 2014-Levothyroxine (L-T4), long the standard of care for treating hypothyroidism, is effective in most patients, but some individuals do not regain optimal health on L-T4 monotherapy.

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