NANOTECHNOLOGY

Long-term treatment success using gene therapy to correct a lethal metabolic disorder

NANOTECHNOLOGY Excessive and often lethal blood levels of bilirubin can result from mutations in a single gene that are the cause of the metabolic disease known as Crigler-Najjar syndrome type 1 (CNS1). A new gene therapy approach to correcting this metabolic error achieved significant, long-lasting reductions in bilirubin levels in a mouse model of CNS1 and is described in an Open Access article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Human Gene Therapy website at http://online.liebertpub.com/doi/full/10.1089/hum.2013.233.

Drug-infused nanoparticle is right for sore eyes

For the millions of sufferers of dry eye syndrome, their only recourse to easing the painful condition is to use drug-laced eye drops three times a day. Now, researchers from the University of Waterloo have developed a topical solution containing nanoparticles that will combat dry eye syndrome with only one application a week.

Coral Bleaching Near Oahu Signals Ecosystem’s Distress

With this summer bringing record-breaking heat waves throughout the northern hemisphere, the people of Hawaii have found that the lack of trade winds have made for a particularly warm and humid summer. And they’re not the only ones suffering.

Toddlers regulate behavior to avoid making adults angry

When kids say "the darnedest things," it's often in response to something they heard or saw. This sponge-like learning starts at birth, as infants begin to decipher the social world surrounding them long before they can speak.

Supervisors' abuse, regardless of intent, can make employees behave poorly

So-called motivational abuse is seen as a violation and leads to behavioral backlash So-called motivational abuse is seen as a violation and leads to behavioral backlash Employees who are verbally abused by supervisors are more likely to "act out" at work, doing everything from taking a too-long lunch break to stealing, according to a new study led by a San Francisco State University organizational psychologist.

Vesicles influence the function of nerve cells

Neurons react to the transmission activity of exosomes on three fundamental levels Neurons react to the transmission activity of exosomes on three fundamental levels Tiny vesicles containing protective substances which they transmit to nerve cells apparently play an important role in the functioning of neurons.

Scientists discover pain receptor on T-cells

Researchers at University of California, San Diego School of Medicine have discovered that T-cells - a type of white blood cell that learns to recognize and attack microbial pathogens - are activated by a pain receptor.

Scientists develop barcoding tool for stem cells

New technology that tracks the origin of blood cells challenges scientific dogma New technology that tracks the origin of blood cells challenges scientific dogma A 7-year-project to develop a barcoding and tracking system for tissue stem cells has revealed previously unrecognized features of normal blood production: New data from Harvard Stem Cell Institute scientists at Boston Children's Hospital suggests, surprisingly, that the billions of blood cells that we produce each day are made not by blood stem cells, but rather their less pluripotent descendants, called progenitor cells.

A new way to extract bone-making cells from fat tissue

PROVIDENCE, R.I. [Brown University] — Within our fat lives a variety of cells with the potential to become bone, cartilage, or more fat if properly prompted. This makes adipose tissue, in theory, a readily available reservoir for regenerative therapies such as bone healing if doctors can get enough of those cells and compel them to produce bone.

Teen hormones and cellphones

Sexting leads to increased sexual behavior among teens Sexting leads to increased sexual behavior among teens Researchers at the University of Texas Medical Branch at Galveston say that sexting may be the new "normal" part of adolescent sexual development and is not strictly limited to at-risk teens.

Why Antimatter Matters—Majorana Particles Discovered By Princeton University

When a long-held theory concerning particle physics lasts 80 years, you can assume that research discoveries are often few and far between. But it turns out that physics may have a new chapter added to the record books as researchers at Princeton University have solved the mystery of “Majorana Particles”.
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