MEDICINE & HEALTH

Exceptional Human-on-a-Chip Predicts in Vivo Results Based on in Vitro Model

According to the pioneers of the human-on-a-chip in vitro system, they announced the use of its unique multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules over time, to accurately describe the drug behavior and toxic effects in vivo. Furthermore, the findings support the potential of body-on-a-chip systems to transform the drug discovery process.

Protein-Linked Sugars are Crucial for the Uptake of Proteins Linked to Parkinson's Disease

The accumulation of alpha-synuclein proteins in the brain is the culprit behind the neurogenerative disorder in Parkinson's disease. Current knowledge cannot explain wholly how alpha-synuclein works, but with its impact in neurogenerative diseases, scientists aim to broaden the knowledge scope on Parkinson's disease and find new treatment methods.

Securing Cell-killing Treatments in Tumors After Injection

Attaching a Velcro-like molecule may prevent immune proteins from leaking out after injection. Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment.

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