Staff Reporter

Longer-term outcomes of program to reduce unnecessary antibiotic prescriptions

The initial benefits of an outpatient antimicrobial stewardship intervention designed to reduce the rate of inappropriate antibiotic prescriptions were lost after discontinuation of audit and feedback to clinicians, according to a study published in JAMA. The study is being released early online to coincide with the IDWeek 2014 meeting.

New meningitis vaccine only cost-effective at low price

The ideal cost per dose for a new meningitis vaccine ranges from £3 up to a possible £22 only if several vaccine favourable factors all coincide, according to research which has analysed how to maximise the reduction in cases while making a new vaccination programme cost-effective.

Mechanism that repairs brain after stroke discovered

A previously unknown mechanism through which the brain produces new nerve cells after a stroke has been discovered at Lund University and Karolinska Institute in Sweden. The findings have been published in the journal SCIENCE.

An unexpected bonus - blocking STAT3 could help cancer patients in two ways

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising.

Nobel Peace Prize Announcement—Less Than An Hour Away, and Here Are the Final Bets

Perhaps one of the most prestigious prizes awarded on a global context, the Nobel Peace Prize has been an enigma since its ambiguous inception. While Alfred Nobel left behind a long legacy and a way for the world to annually commemorate the greatest minds each generation comes to find, there has been a large breadth of past winners, leaving the annual guessing game of who’s on the short list and who’s going to win a toss-up in most peoples’ eyes. But to make an accurate guess you have to know the facts.
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