Mayo Clinic Breakthrough With ALS Treatment In Mice

Researchers at the Jacksonville, Florida Mayo Clinic have gained a mouse model for testing potential amyotrophic lateral sclerosis (ALS) treatments. ALS or Lou Gehrig's disease is associated with various behavioral features and neuropathological symptoms as is frontotemporal dementia (FTD); both are caused by a mutation in the C9ORF72 gene. Both result in the death of neurons in the spinal cord and brain, which leads to inability to control muscles, paralysis, and death.
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