Researchers discovered an affordable tool with bristles that may reduce hospital-acquired pneumonia rates, particularly for patients on mechanical ventilation.

The study, titled "Association Between Daily Toothbrushing and Hospital-Acquired Pneumonia" published in JAMA Internal Medicine, analyzed 15 trials, involving over 2,700 patients, showing lower pneumonia rates among those practicing daily toothbrushing. The findings show potential life-saving benefits, underscoring the importance of regular toothbrushing in hospitals.

Daily Toothbrushing in Hospitals Reduces Pneumonia, Improves Patient Outcomes
(Photo : Pixabay/Martin Slavoljubovski)
Daily Toothbrushing in Hospitals Reduces Pneumonia, Improves Patient Outcomes

Hospital-Acquired Pneumonia (HAP) Symptoms, Causes, and Risks

Hospital-acquired pneumonia (HAP), emerging at least 48 hours post-hospitalization, poses a substantial health threat, with gram-negative bacilli and Staphylococcus aureus as prevalent pathogens.

Symptoms include malaise, fever, cough, and chest pain, diagnosed through clinical presentation and confirmatory tests. Antibiotics are vital, but prognosis is often poor due to comorbidities.

Approximately 1 in 100 hospitalized patients develop HAP, risking prolonged recovery and heightened treatment costs. Mechanical ventilation escalates the risk, especially for intubated patients, while non-ventilated individuals contribute significantly to HAP cases.

Causes include microaspiration of oropharyngeal bacteria, bacteremia seeding, or inhalation of contaminated aerosols. Risk factors encompass prior antibiotic use, high gastric pH, and underlying cardiac, pulmonary, hepatic, or renal insufficiency. More so, people aged over 70, patients who had abdominal/thoracic surgery, and functional debilitation heightened postoperative pneumonia risks.

Despite effective antibiotics, HAP-associated mortality remains high, often intertwined with underlying illnesses. Adequate initial antimicrobial therapy improves prognosis, but antibiotic-resistant bacteria worsen outcomes.

READ ALSO: Explainable AI Accurately Labels X-Ray Images of Five Chest Pathologies Equivalent to Seven Human Experts

How Toothbrushing Helps Prevent HAP

HAP occurs when oral bacteria infiltrate a patient's airways, posing a heightened risk for frail or immunocompromised individuals during their hospital stay. Fortunately, the new study shows that implementing a daily toothbrushing regimen holds promise in diminishing oral bacteria, potentially reducing the likelihood of hospital-acquired pneumonia.

To investigate the relationship between daily toothbrushing and hospital-acquired pneumonia, researchers conducted a comprehensive review and meta-analysis.

By examining randomized clinical trials from various global databases, the study compared the effects of regular oral care with toothbrushing against oral care without toothbrushing, focusing on the incidence of hospital-acquired pneumonia and related outcomes.

The analysis yielded significant findings, indicating that daily toothbrushing was associated with a notable decrease in the risk of hospital-acquired pneumonia and ICU mortality. Additionally, patients in the ICU who practiced toothbrushing exhibited fewer days of mechanical ventilation and a shorter ICU length of stay.

While the majority of studies concentrated on tooth-cleaning regimens for adults in the ICU, only two of the 15 studies in the analysis explored the impact of toothbrushing in non-ventilated patients.

The researchers express optimism regarding the potential protective effect of toothbrushing extending to non-ICU patients. However, they underscore the need for additional studies dedicated to this specific population to confirm this hypothesis.

Emphasizing the importance of incorporating an oral health routine involving toothbrushing for hospitalized patients, the researchers hope their study will encourage the development of policies and programs ensuring regular teeth brushing, even with assistance from the patient's care team if needed.

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